Lab Test

Test Definition Number : 37
Test Definition Name : BCR-ABL1 t(9;22) translocation detection
Lab Name : Hospital of the University of Pennsylvania
Lab Test Number of THIS Version : 1072
Lab Test Name : BCR-ABL1 Qualitative RT-PCR
Status : Active
Expired : No
Updated : 2017-03-03 16:59 EST

General Attributes

Chromosome Band : 9q34.11
22q11.22
HUGO Gene Name : [ABL1] ABL proto-oncogene 1, non-receptor tyrosine kinase
[BCR] breakpoint cluster region
ICD-Oncology Code
(includes WHO classification diagnoses)
: [9875/3] Chronic myelogenous leukemia, BCR/ABL positive

Infectious Disease Attributes

Agent Category :
Non-virus Genus and Species :
Virus Family, Genus, and Species :

Lab-specific Attributes

Method : Electrophoresis - Agarose Gel
Polymerase Chain Reaction (PCR) - Reverse Transcriptase
Specimen Source
(for clinical patient care these sources must be validated)
: Aspirate - Bone Marrow
Blood - Whole Blood
ICD-10 Code :
Use : Clinical - CLIA-certified lab
Genetics Category : Acquired (somatic)
SNOMED CT :
LOINC : [63422-0] "t(9;22)(q34.1;q11)(ABL1,BCR) b2a2+b3a2+e1a2 fusion transcript"
Comments : This assay detects the fusion transcripts associated with the major (p210) breakpoints, as well as the fusion transcript associated the with minor (p190) breakpoint in BCR-ABL1. Fusion transcripts with rare breakpoints may not be detected.
Specimen Transport Requirements :
Samples Available for Proficiency Test Sample Exchange : No

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