Lab Test

Test Definition Number : 199
Test Definition Name : PML-RARA t(15;17) translocation detection
Lab Name : Hospital of the University of Pennsylvania
Lab Test Number of THIS Version : 1074
Lab Test Name : PML-RARA Qualitative RT-PCR
Status : Active
Expired : No
Updated : 2017-03-03 16:59 EST

General Attributes

Chromosome Band : 15q24.1
HUGO Gene Name : [PML] promyelocytic leukemia
[RARA] retinoic acid receptor, alpha
ICD-Oncology Code
(includes WHO classification diagnoses)

Infectious Disease Attributes

Agent Category :
Non-virus Genus and Species :
Virus Family, Genus, and Species :

Lab-specific Attributes

Method : Electrophoresis - Agarose Gel
Polymerase Chain Reaction (PCR) - Reverse Transcriptase
Specimen Source
(for clinical patient care these sources must be validated)
: Aspirate - Bone Marrow
Blood - Whole Blood
ICD-10 Code :
Use : Clinical - CLIA-certified lab
Genetics Category : Acquired (somatic)
LOINC : [21551-7] "t(15;17)(q24.1;q21.1)(PML,RARA) fusion transcript"
Comments : This assay detects PML-RARA fusion transcripts including those resulting from intron 3 (short, bcr-3), intron 6 (long, bcr-1), and the majority of exon 6 (variable, bcr-2) breakpoints in PML. Rare variant RARA rearrangements are NOT detected by this assay.
Specimen Transport Requirements :
Samples Available for Proficiency Test Sample Exchange : No


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