Lab Test

Test Definition Number : 275
Test Definition Name : DRD3 sequence analysis
Lab Name : Mayo Clinic Personalized Genomics Laboratory
Lab Test Number of THIS Version : 1217
Lab Test Name : Dopamine Receptor D3 Genotype
Status : Active
Expired : No
Updated : 2018-05-17 06:59 EDT

General Attributes

Chromosome Band : 3q13.31
HUGO Gene Name : [DRD3] dopamine receptor D3
ICD-Oncology Code
(includes WHO classification diagnoses)

Infectious Disease Attributes

Agent Category :
Non-virus Genus and Species :
Virus Family, Genus, and Species :

Lab-specific Attributes

Method : Polymerase Chain Reaction (PCR) - Allele-Specific
Specimen Source
(for clinical patient care these sources must be validated)
: Blood - Whole Blood
ICD-10 Code :
Use : Clinical - CLIA-certified lab
Clinical - certified for NY patients
Genetics Category : Pharmacogenetics
Comments : HUGO Gene Name: DRD3 See Useful For: -Influencing choice of antipsychotics prior to treatment, especially to ascertain if atypical antipsychotics may be used with low risk of tardive dyskinesia -Identifying those patients receiving antipsychotics who are at increased risk of developing tardive dyskinesias. Individuals with the 25G allele should be monitored closely for signs of tardive dyskinesia if a decision is made to treat with antipsychotics. -Testing may also be considered for individuals who will receive antipsychotic medications, if they are first-degree relatives of patients who have developed tardive dyskinesia. -Assessing potential for effective treatment response with clozapine, olanzapine, and risperidone
Specimen Transport Requirements :
Samples Available for Proficiency Test Sample Exchange : No


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